Saturday, October 13, 2018

prostate cancer | In case of localized cancer





In case of localized cancer





There are several ways to treat prostate cancer:
Surgery is to remove the prostate and the seminal vesicles (radical prostatectomy)
External radiation: Rays sent by a machine to the outside of the body by irradiation beams converging in the prostate. It is done in the form of short sessions each day, for a total treatment period of 7 to 8 weeks

Brachytherapy (internal radiation therapy):
Two techniques are currently proposed to Gustave Rousse:

Classical treatment with small radioactive grains permanently implanted in the prostate using needles under general anesthesia
High-flow treatment, which consists of temporarily introducing catheters into the prostate, in which a microsource of Iridium 192 delivers very high radioactive doses. This treatment is usually provided in two sessions, prior to external radiation therapy.
More information on brachytherapy

Drug treatments are based on the use of:

Hormone therapy (LH-RH analogs: administered by injection every 3 months or anti-androgenic peripherals administered by the mouth).
Chemotherapy, which is usually administered by venous means.
Isolated biochemical Relapse
The patient in isolated biochemical relapse (PSA rate recovery) after surgery is treated either by remedial radiation therapy on the Prostatectomy Lodge or by hormone therapy: Different therapeutic trials are underway on this subject and Could be offered to you.
After external radiation therapy and after brachytherapy, the patient in biochemical relapse is treated according to the rate of reascent of PSA: hormone therapy or simple surveillance can be proposed.

Metastatic prostate Cancer
Most often the metastases of prostate cancer lie at the level of the lymph nodes and the bone. metastases correspond to tumor cells manufactured at the prostate level and have gone into other organs by being transported either by blood or through the lymph channels.

Initial treatment of metastases of prostate cancer is based on a hormonal treatment that has the primary goal of lowering the rate of testosterone (male hormone) in the blood. This hormonal treatment is based either on subcutaneous or intra-muscular injections (monthly or every three months) or on a surgical procedure involving the testicles. Treatment in the form of anti-hormonal tablets (peripheral anti-androgens) can be associated.

As the disease is resistant to hormonal treatment, several measures will be discussed:

Either a change in hormonal treatment
Chemotherapy using the Docetaxel, if necessary reinforced by the Estramustine
The use of bone treatment in the form of monthly intra-venous infusion (zoledronic acid)
Moreover, many promising drugs are available in this situation, in the context of clinical trials conducted in Gustave Rousse.

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